Dendritic tree extraction (DTE) method. For an example MIP image (a), we show the outcome after computing posterior probability, Eq. (3) in (b). Low values are red while higher values appear darker. (c) depicts the outcome after the optimized sensitivity threshold is applied to (b) to obtain a coarse segmentation. (d) Results after the automatic refinement and post-processing steps. Red arrows indicate examples of remaining artifacts, as a result of the presence of granules, around the cell body (soma) and tree.