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Table 2 The top half of the table displays the increasing cohort and per patient median insulin sensitivity over 6hr blocks and the second half of the table shows the reductions in the IQR and median per-patient hour to hour percentage insulin sensitivity over time

From: Reducing the impact of insulin sensitivity variability on glycaemic outcomes using separate stochastic models within the STAR glycaemic protocol

SI level analysis

Cohort analysis

Per-patient analysis

% increase at median

p-value

% increase at median

p-value

0-6 vs 6–12 hrs

42

< 0.0001

40

0.0007

6-12 vs 12–18 hrs

28

<0.0001

26

0.0123

12-18 vs 18–24 hrs

1

0.0335

3

0.4822

18-24 vs 24–48 hrs

9

0.0428

7

0.2873

Variability analysis

% Change of IQR

p-value

% Change at median

p-value

0-6 vs 6–12 hrs

-36

0.0092

-39

<0.0001

6-12 vs 12–18 hrs

-24

0.0806

-29

0.0794

12-18 vs 18–24 hrs

1

0.0806

-9

0.1029

18-24 vs 24–48 hrs

-19

0.0998

-18

0.0467

  1. P-values calculated using Kolmogorov-Smirnov test for cohort comparisons and Wilcoxon rank-sum for per-patient comparisons.