Electrochemotherapy: from the drawing board into medical practice

Table 2 Response rate of the tumors treated by electrochemotherapy, pooled from individual studies

Publication period	No. of studies	No. of patients	No. of tumors	OR (%)	CR (%)	PR (%)	NR (%)
Before SOP	19	175	592	458 (77.4%)^{a, b}	362 (61.1%)	96 (16.3%)^{c, d}	134 (22.6%)^{e, f}
ESOPE	1	41	171	145 (84.8%)	126 (73.7%)	19 (11.1%)	26 (15.2%)
After SOP (Oct 2011)	25	294	1192	1047 (87.8%)^a	712 (59.7%)	335 (28.1%)^c	145 (12.2%)^e
After SOP (Aug 2013)	41	519	1664	1478 (88.8%)^b	1031 (62.0%)	447 (26.9%)^d	186 (11.2%)^f

The studies are grouped in those before, and after the ESOPE study, when the standard operating procedures were published, in 2006. OR = objective response (complete response + partial response); CR = complete response; PR = partial response; NR = no response (no change + progressive disease); ^{a, b, c, d, e, f} = statistically significant difference (p < 0.001, Chi-square test).

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