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Table 6 Comparisons of number of segmented cells and classification performance between proposed method and CellProfiler evaluated based on PVO, PVD, RAE, and MHD.

From: An automatic segmentation and classification framework for anti-nuclear antibody images

Pattern

Detected Cell Number

PVO (%)

PVD (%)

RAE ± Std.

MHD ± Std.

 

G. Truth

Proposed

CellProfiler

Proposed

CellProfiler

Proposed

CellProfiler

Proposed

CellProfiler

Proposed

CellProfiler

Diffuse

251

157

107

87.89

84.75

24.23

30.50

0.6386 ± 0.42

0.5248 ± 0.36

250.90 ± 228.42

510.69 ± 250.56

Peripheral

191

153

97

93.47

72.43

13.06

55.15

0.3039 ± 0.35

0.5120 ± 0.31

87.15 ± 182.86

602.36 ± 267.78

Nucleolar

285

175

101

91.94

84.90

16.12

30.20

0.4777 ± 0.41

0.6445 ± 0.33

157.99 ± 208.70

560.73 ± 225.77

Coarse speckled

363

260

150

92.35

87.84

15.31

24.32

0.3506 ± 0.36

0.7038 ± 0.21

101.90 ± 199.74

556.02 ± 261.51

Fine speckled

117

67

36

91.27

91.22

17.46

17.55

0.5423 ± 0.41

0.8637 ± 0.13

173.20 ± 13.16

458.46 ± 21.41

Discrete speckled

216

195

125

78.03

69.64

43.95

60.71

0.5457 ± 0.37

0.7277 ± 0.18

143.99 ± 202.59

504.55 ± 242.68