A computer model of lens structure and function predicts experimental changes to steady state properties and circulating currents

Table 4 Comparison of inhibiting Na ⁺ /K ⁺ pump rate either computationally or experimentally using Ouabain

Species	Temperature dependent % reduction in pump rate	% Reduction current density
Species	Temperature dependent % reduction in pump rate	Ap	Eq	Pp
Mouse	28% (T = 300°K)	50%	50%	50%
Model	82% (T = 280°K)	100%	100%	100%
	Pharmacological inhibition of pump rate Ouabain (mM)
Frog [16]	0.1 mM	50%	70%	40%
Rabbit [15]	0.1 mM	60%	60%	60%
Rat [9]	1 mM	100%	100%	100%

ISSN: 1475-925X