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Table 4 Comparison of inhibiting Na + /K + pump rate either computationally or experimentally using Ouabain

From: A computer model of lens structure and function predicts experimental changes to steady state properties and circulating currents

Species Temperature dependent % reduction in pump rate % Reduction current density
Ap Eq Pp
Mouse 28% (T = 300°K) 50% 50% 50%
Model 82% (T = 280°K) 100% 100% 100%
  Pharmacological inhibition of pump rate Ouabain (mM)  
Frog [16] 0.1 mM 50% 70% 40%
Rabbit [15] 0.1 mM 60% 60% 60%
Rat [9] 1 mM 100% 100% 100%