Figure 7
Comparison of the effects of depolarization and reduction in Na + pump rate on intracellular ion concentration gradients. A-C: 2D plots of the radially extracted intracellular concentration gradients for Na + (A), K + (B) and Cl- (C) obtained by solving the model using extracellular K + concentrations of 8 (●), 58 (■) and 108 mM (▲) as the boundary conditions to mimic lens Em depolarization. D-F: 2D plots of the radially extracted intracellular concentration gradients for Na + (D), K + (E) and Cl- (F) obtained by solving the model using temperatures of 310 (●), 300 (■) and 280°K (▲) as the starting boundary conditions to mimic a reduction in Na + pump rate.