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Table 4 The results of the combined method

From: Fourier domain closed-form formulas for estimation of kinetic parameters in reversible multi-compartment models

Case

K 1(min -1)

k 2(min -1)

k 3(min -1)

k 4(min -1)

K 1 (k 3 + k 4 ) /(k 2 k 4 )

K 1 k 3 /(k 2 k 4 )

k 3 /k 4

α = 0

0.40

0.30

0.20

0.10

4.00

2.67

2.00

α = 0.1

0.40 ± 0.00

0.30 ± 0.01

0.20 ± 0.01

0.10 ± 0.00

4.00 ± 0.02

2.67 ± 0.05

2.01 ± 0.11

α = 0.4

0.40 ± 0.02

0.31 ± 0.07

0.21 ± 0.06

0.10 ± 0.01

4.01 ± 0.08

2.68 ± 0.19

2.07 ± 0.46

True

0.40

0.30

0.20

0.10

4.00

2.67

2.00

  1. The output of the proposed closed-form method is used as the initial condition of the iterative method. The number of noise realization is 250.
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