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Table 3 The results of the combined method

From: Fourier domain closed-form formulas for estimation of kinetic parameters in reversible multi-compartment models

Case

Stage 1: Fourier method output

Stage 2: Final iterative method output

K 1(min -1)

k 2(min -1)

k 3(min -1)

k 4(min -1)

K 1(min -1)

k 2(min -1)

k 3(min -1)

k 4(min -1)

α = 0

0.39

0.27

0.17

0.09

0.40

0.30

0.20

0.10

α = 0.1

0.39

0.27

0.11

0.09

0.40

0.28

0.18

0.10

α = 0.4

0.38

0.23

0.14

0.09

0.42

0.35

0.28

0.12

True

0.40

0.30

0.20

0.10

0.40

0.30

0.20

0.10

  1. The output of the proposed closed-form method is used as the initial condition of the iterative method. One noise realization is used.