Trend plots of mean ICP/mean ICP wave amplitude of Signals 1 and 2 (PatID 12). The trend plots of mean ICP and mean ICP wave amplitude (MWA) of (a) Signal 1 and (b) Signal 2 of PatID 12 is shown [Average of mean ICP: 6.8 mmHg (Signal 1), 11.9 mmHg (Signal 2). Average of mean ICP wave amplitude: 5.6 mmHg (Signal 1), 5.7 mmHg (Signal 2)]. The vertical arrow in (b) indicates a shift in mean ICP without accompanying change in MWA. The shift of mean ICP in (b) was not accompanied by a simultaneous shift in mean ICP in (a).