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Figure 8 | BioMedical Engineering OnLine

Figure 8

From: A new electric method for non-invasive continuous monitoring of stroke volume and ventricular volume-time curves

Figure 8

Schematics illustrating the relation between a volume change of some blood filled lumen (such as e.g. a ventricle) and the sum of dipoles that represent the first order alteration of the E-field due to the volume change, as explained in the first subsection of the Appendix. a: The initial volume of blood (at τ=0) is bounded by a closed surface A 0 (indicated by the dashed line) that has non-zero values of s 0. At each surface element δ A i of the surface A 0 , there is a charge q i that is proportional to (E 0 · δ A i ). The charges on the boundary surface A 0 are indicated by the and signs. (Evidently, in an applied AC current field, the boundary charges change signs continuously, along with the direction of the arrow of the applied E 0, with the same frequency f of the AC current. In this schematic however, only the moments in time are depicted in which the arrows point in one specific direction). b: Situation at some time τ>0during the same cardiac cycle. The volume of blood has become smaller, and is now bounded by the non-zero values of s(τ). c: Subtraction of the volumes from (a) and (b), in which the volume difference V(τ)−V(0)is indicated by the grey shade. If the voltage distributions on the thoracic skin in situation (a) and (b) are denoted by Φ(x,0)and Φ(x,τ), respectively, then the voltage change Φ(x,τ)−Φ(x,0)corresponds to s(x,τ)−s 0(x), and hence also corresponds to the dipoles in (b) minus the dipoles in (a). d: The grey-shaded volume difference V(τ)−V(0)equals the sum of a set of small rectangular beams : V(τ)V(0)= i h i · δ A i , which is quite similar to the sum of the dipoles formed by the charges at the end-points of the rectangular beams, corresponding to the dipole interpretation of the charges in (c).

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