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Table 5 Comparison of pupillometric parameters between the two follow-up time-points in subject 2 (Both Tests)

From: Pupillometric analysis for assessment of gene therapy in Leber Congenital Amaurosis patients

Par.

Test 1

Test 2

 

1 year time-point

3 year time-point

 

1 year time-point

3 year time-point

 
 

Med

25 th

75 th

Med

25 th

75 th

P

Med

25 th

75 th

Med

25 th

75 th

P

BD

5.15

4.30

5.77

4.92

3.82

5.62

<0.01

4.99

4.26

5.23

4.67

4.19

5.13

0.55

MA

5.05

4.11

5.57

4.71

3.71

5.50

<0.01

4.65

4.05

4.97

4.36

3.88

4.90

0.48

RA

0.17

0.06

0.28

0.11

0.04

0.22

0.24

0.24

0.05

0.34

0.24

0.05

0.43

0.53

PC

0.97

0.95

0.99

0.97

0.96

0.99

0.68

0.95

0.93

0.99

0.95

0.90

0.99

0.54

RT

0.62

0.20

1.06

0.72

0.52

1.08

0.30

1.04

0.56

1.50

1.10

0.70

1.34

0.80

CV

0.26

0.13

0.34

0.15

0.07

0.26

0.38

0.20

0.09

0.34

0.21

0.05

0.44

0.89

  1. Par: parameters.
  2. Med: median.
  3. 25th : 25 th percentile (first quartile)/75th : 75 th percentile (third quartile).
  4. P: p-value.