Table 3 Semiquantitative scoring of Toluidine blue stained slices

Assessment of the bone structure (cavities)

regular

0

minor irregularities (< 30% of surface)

1

distinct irregularities (30 to 60% of surface)

2

severe irregularities (< 60% of surface)

3

Periosteal remodelling

none

0

thickness equals 1 osteon

1

thickness equals 2 osteons

2

thickness equals 3 osteons

3

Endosteal remodelling

none

0

thickness equals 1 osteon

1

thickness equals 2 osteons

2

thickness equals 3 osteons

3

Endosteal formation of new bone

none

0

< 1/3 of the endosteal surface

1

1/3 to 2/3 of the endosteal surface

2

> 2/3 of the endosteal surface

3

Periosteal formation of new bone

none

0

< 1/3 of the periosteal surface

1

and < 1/3 of the cortical thickness

1/3 to 2/3 of the periosteal surface

2

or 1/3 to 2/3 of the cortical thickness

> 2/3 of the periosteal surface

3

or > 2/3 of the cortical thickness