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Table 2 Summary of correlation results between plaque wall stress (PWS) and plaque progression from 32 scan pairs using both baseline/follow-up scans and maximum and minimum flow rates in a cardiac cycle

From: Impact of flow rates in a cardiac cycle on correlations between advanced human carotid plaque progression and mechanical flow shear stress and plaque wall stress

Case #	# of Data Pts	PWS Baseline Max-Q		PWS Baseline Min-Q		PWS Follow-Up Max-Q		PWS Follow-Up Min-Q
		r	p	r	p	r	p	r	p
C1	400	-0.060	0.232	-0.059	0.243	-0.301	< .001	-0.299	< .001
C2	400	0.192	< .001	0.192	< .001	-0.209	< .001	-0.209	< .001
C3	900	0.019	0.564	0.022	0.505	-0.440	< .001	-0.437	< .001
C4	400	0.467	< .001	0.469	< .001	-0.079	0.116	-0.085	0.091
C5	800	0.270	< .001	0.260	< .001	-0.108	0.002	-0.129	< .001
C6	800	-0.039	0.274	-0.023	0.508	-0.279	< .001	-0.275	< .001
C7	800	0.133	< .001	0.145	< .001	-0.179	< .001	-0.166	< .001
C8	800	0.267	< .001	0.263	< .001	-0.133	< .001	-0.141	< .001
C9	600	0.457	< .001	0.457	< .001	0.208	< .001	0.208	< .001
C10	600	-0.297	< .001	-0.297	< .001	-0.622	< .001	-0.622	< .001
C11	700	-0.048	0.208	-0.043	0.252	-0.325	< .001	-0.329	< .001
C12	700	-0.024	0.530	-0.015	0.695	-0.228	< .001	-0.218	< .001
C13	600	-0.119	0.004	-0.120	0.003	-0.229	< .001	-0.242	< .001
C14	1000	-0.098	0.002	-0.097	0.002	-0.341	< .001	-0.342	< .001
C15	1000	0.235	< .001	0.240	< .001	-0.101	0.001	-0.100	0.002
C16	900	-0.037	0.269	-0.037	0.262	-0.302	< .001	-0.307	< .001
C17	800	-0.125	< .001	-0.121	< .001	-0.386	< .001	-0.383	< .001
C18	800	0.030	0.397	0.030	0.396	-0.368	< .001	-0.369	< .001
C19	800	-0.017	0.632	-0.016	0.649	-0.228	< .001	-0.228	< .001
C20	800	0.492	< .001	0.491	< .001	0.253	< .001	0.252	< .001
C21	900	0.097	0.004	0.094	0.005	-0.080	0.016	-0.081	0.015
C22	900	-0.135	< .001	-0.135	< .001	-0.241	< .001	-0.241	< .001
C23	700	0.408	< .001	0.412	< .001	-0.144	< .001	-0.143	< .001
C24	800	0.242	< .001	0.242	< .001	-0.402	< .001	-0.403	< .001
C25	800	0.227	< .001	0.226	< .001	-0.374	< .001	-0.375	< .001
C26	700	0.107	0.005	0.107	0.005	-0.221	< .001	-0.220	< .001
C27	700	0.024	0.531	0.019	0.609	-0.416	< .001	-0.415	< .001
C28	900	0.470	< .001	0.470	< .001	-0.011	0.741	-0.014	0.673
C29	900	0.080	0.017	0.087	0.009	0.013	0.694	0.016	0.639
C30	800	0.110	0.002	0.112	0.002	-0.052	0.140	-0.051	0.152
C31	800	0.127	< .001	0.125	< .001	-0.149	< .001	-0.154	< .001
C32	800	0.119	0.001	0.117	< .001	-0.158	< .001	-0.161	< .001
Positive		18		18		2		2
Negative		5		5		26		26
No Signifi.		9		9		4		4
95% CI		(0.039, 0.184)		(0.041, 0.185)		(-0.273, -0.142)		(-0.273, -0.143)

New correlation results from the 32 pairs indicated that advanced plaque progression correlated with PWS negatively using follow-up scans and positively using baseline scans. Flow rates had almost no impact on those correlations.

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ISSN: 1475-925X

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