Figure 9

The transition diagrams and the posterior probabilities of the reduced feature space after mRMR and AICc. (a) The state transition diagram for HMM_AIC is given. Similar to the HMM_opt14D, the some early tonic activity permissive to seizures is allowed to return to the interictal state. Between the late tonic firing and postictal state, the transition follows a unidirectional progression. (b) The mapping of HMM_AIC states to the electrophysiological LFP is shown. In this illustrative example, the marginal probabilities of the model states follow a progression from non-ictal, tonic firing to chronic seizures and postictal state, before returning to non-ictal. The late tonic firing state in this model is typically shorter than the model from Figure 5b because of the significantly smaller transition probability back to itself.