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Figure 10 | BioMedical Engineering OnLine

Figure 10

From: Wavelet-based Gaussian-mixture hidden Markov model for the detection of multistage seizure dynamics: A proof-of-concept study

Figure 10

The relationship between the HMM identified late tonic states and the intracellular modes. (a) The temporal relationship between the intracellular modes before chronic seizures and the HMM late tonic firing states for each SLE in the test set is shown. The intracellular modes are shown in solid color (red for prem and blue for pred). The identified states by the HMM are shown as dashed lines (red for early tonic and blue for late tonic states). (b) The boxplot summarizes the relationship between the start of the pred intracellular activity and the onset of the late tonic firing model state. The HMM was able to identify 85.9% of the pred activity as the late tonic firing state. The mean starting times for the electrographical pred activity and the model late tonic state were 16.25 s and 16.77 s prior to chronic seizure onset, respectively. Using pair-wise T-test analysis, no statistically significant difference was found between the two (p > 0.49).

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