MRI and corresponding neuropathology of rat brain tissue lesioned with H-FIRE and IRE. Top Panels (A-C) obtained from Rat #3, in which both the right (Panel B) and left (Panel C) cerebral hemispheres were treated with H-FIRE at 400 V/250 kHz and 300 V/250 kHz, respectively. Bottom Panels (D-F), Rat #4, which underwent H-FIRE in the right cerebrum at 400 V/500 kHz (Panel E), and IRE in the left cerebrum at 50 V (Panel F). Panels A and D are the same as those presented in Figure 7A and D, with an outline of the lesions that are further represented in Panels B, C, E, and F (Hematoxylin and eosin stain, bar = 1 mm). In Panels B, C, E, and F, the delineation between treated and untreated tissue is shown (black, dotted line). In Panels A and D, the right side of the brain is on the left side of the panel.