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  1. The impact of the pandemic caused by the coronavirus (SARS-CoV-2), causing the disease COVID-19, has brought losses to the world in terms of deaths, economic and health problems. The expected return of the pub...

    Authors: Suelia de Siqueira Rodrigues Fleury Rosa, Ana Karoline Almeida da Silva, Carolina Ramos dos Santos, Mayla dos Santos Silva, Ana Luísa Pereira Perillo, Arthur Faria Mendonça, Mario Fabrício Fleury Rosa, Thatiane Lima Sampaio, Marcella Lemos Brettas Carneiro, José Carlos Tatmatsu Rocha, Antônio Piratelli-Filho and Allisson Lopes de Oliveira
    Citation: BioMedical Engineering OnLine 2022 21:84
  2. Tooth demineralization is one of the most common intraoral diseases, encompassing (1) caries caused by acid-producing bacteria and (2) erosion induced by acid of non-bacterial origin from intrinsic sources (e....

    Authors: Fatin Najwa Mohamad Saberi, Prema Sukumaran, Ngie Min Ung and Yih Miin Liew
    Citation: BioMedical Engineering OnLine 2022 21:83
  3. Surgical video phase recognition is an essential technique in computer-assisted surgical systems for monitoring surgical procedures, which can assist surgeons in standardizing procedures and enhancing postsurg...

    Authors: Lixin Fang, Lei Mou, Yuanyuan Gu, Yan Hu, Bang Chen, Xu Chen, Yang Wang, Jiang Liu and Yitian Zhao
    Citation: BioMedical Engineering OnLine 2022 21:82
  4. Since both essential tremor (ET) and Parkinson’s disease (PD) are movement disorders and share similar clinical symptoms, it is very difficult to recognize the differences in the presentation, course, and trea...

    Authors: FuChao Cheng, YuMei Duan, Hong Jiang, Yu Zeng, XiaoDan Chen, Ling Qin, LiQin Zhao, FaSheng Yi, YiQian Tang and Chang Liu
    Citation: BioMedical Engineering OnLine 2022 21:81
  5. Accurate evaluation of the mechanical properties of trabecular bone is important, in which the internal bone marrow plays an important role. The aim of this systematic review is to investigate the roles of bon...

    Authors: Fangxing Wang, Florian Metzner, Georg Osterhoff, Leyu Zheng and Stefan Schleifenbaum
    Citation: BioMedical Engineering OnLine 2022 21:80
  6. The pathological features of cerebral edema are complicated. The intracranial pressure (ICP) is regarded as the most important indicator for monitoring cerebral edema. Recently, multi-parameter has been used t...

    Authors: Weitao Li, Yameng Zhang, Qian Xie, Xinping Qi, Liuye Yao, Xue Ning and Zhiyu Qian
    Citation: BioMedical Engineering OnLine 2022 21:79
  7. Fecal microbial transplantation has emerged in recent years as a method of treating disease by rebuilding the intestinal flora. However, few bibliometric analyses have systematically studied this area of resea...

    Authors: Jing Ma, Ting Chen, Xiangxue Ma, Beihua Zhang, Jiaqi Zhang, Lin Xu, Yifan Wang, Jinke Huang, Zhihong Liu, Fengyun Wang and Xudong Tang
    Citation: BioMedical Engineering OnLine 2022 21:78
  8. To use deep learning of serial portable chest X-ray (pCXR) and clinical variables to predict mortality and duration on invasive mechanical ventilation (IMV) for Coronavirus disease 2019 (COVID-19) patients.

    Authors: Hongyi Duanmu, Thomas Ren, Haifang Li, Neil Mehta, Adam J. Singer, Jeffrey M. Levsky, Michael L. Lipton and Tim Q. Duong
    Citation: BioMedical Engineering OnLine 2022 21:77
  9. Ex-vivo myography enables the assessment of muscle electrical activity response. This study explored the viability of determining the physiological responses in muscles without tendon, as rectus abdominis muscle ...

    Authors: David R. A. Reyes, Angelica M. P. Barbosa, Floriano F. Juliana, Quiroz B. C. V. Sofia, Sarah M. B. Costa, Raghavendra L. S. Hallur, Eusebio M. A. Enriquez, Rafael G. Oliveira, Patricia de Souza Rossignolli, Cristiane Rodrigues Pedroni, Fernanda C. B. Alves, Gabriela A. Garcia, Joelcio F. Abbade, Carolina N. F. Carvalho, Luis Sobrevia, Marilza V. C. Rudge…
    Citation: BioMedical Engineering OnLine 2022 21:76
  10. Capacitively coupled electrode (CC electrode), as a non-contact and unobtrusive technology for measuring physiological signals, has been widely applied in sleep monitoring scenarios. The most common implementa...

    Authors: Shun Peng, Yang Li, Rui Cui, Ke Xu, Yonglin Wu, Ming Huang, Chenyun Dai, Toshiyo Tamur, Subhas Mukhopadhyay, Chen Chen and Wei Chen
    Citation: BioMedical Engineering OnLine 2022 21:75
  11. Hemodialysis complications remain a critical threat among dialysis patients. They result in sudden termination of the session which impacts the efficiency of dialysis. As intra-dialytic complications are the r...

    Authors: Mai Othman, Ahmed Mustafa Elbasha, Yasmine Salah Naga and Nancy Diaa Moussa
    Citation: BioMedical Engineering OnLine 2022 21:74
  12. To verify a test prototype of a novel flexible video laryngoscope in a difficult airway management simulator and to compare the efficacy of the flexible video laryngoscope with that of a conventional video lar...

    Authors: Fei Xu, Chang Liu, Yang Zhou, Min Li and Xiangyang Guo
    Citation: BioMedical Engineering OnLine 2022 21:73
  13. Accurate segmentation of unruptured cerebral aneurysms (UCAs) is essential to treatment planning and rupture risk assessment. Currently, three-dimensional time-of-flight magnetic resonance angiography (3D TOF-...

    Authors: Meng Chen, Chen Geng, Dongdong Wang, Zhiyong Zhou, Ruoyu Di, Fengmei Li, Sirong Piao, Jiajun Zhang, Yuxin Li and Yakang Dai
    Citation: BioMedical Engineering OnLine 2022 21:71
  14. Osteoporosis is a condition characterized by low bone mineral density, which typically leads to fractures and reduced quality of life. Currently, diagnostic devices used to assess this condition (e.g., dual-en...

    Authors: Gabriela Albuquerque, Agnaldo Cruz, Dionísio Carvalho, Nadja Mayrink, Bruno Pinheiro, Antonio Campos, Josivan Gomes Lima, Jorge Henriques and Ricardo Valentim
    Citation: BioMedical Engineering OnLine 2022 21:70
  15. Remote photoplethysmography (rPPG) is a technique developed to estimate heart rate using standard video cameras and ambient light. Due to the multiple sources of noise that deteriorate the quality of the signa...

    Authors: Deivid Botina-Monsalve, Yannick Benezeth and Johel Miteran
    Citation: BioMedical Engineering OnLine 2022 21:69
  16. Medial compartment knee osteoarthritis (KOA) accounts for most KOA cases, and increased trabecular bone volume fraction (BV/TV) is one of the pathological changes in the tibial plateau of KOA. How BV/TV change...

    Authors: Liqin Zheng, Yuexing Dai, Yongze Zheng, Xingpeng He, Minhui Wu, Desheng Zheng, ChiHung Li, Yueguang Fan and Ziling Lin
    Citation: BioMedical Engineering OnLine 2022 21:68
  17. Facial paralysis (FP) is an inability to move facial muscles voluntarily, affecting daily activities. There is a need for quantitative assessment and severity level classification of FP to evaluate the conditi...

    Authors: Amira Gaber, Mona F. Taher, Manal Abdel Wahed, Nevin Mohieldin Shalaby and Sarah Gaber
    Citation: BioMedical Engineering OnLine 2022 21:65
  18. Estimating relative tidal volume is an important factor when monitoring breathing status. The relationship between temperature and respiration volume has rarely been studied. In this paper, a formula was deriv...

    Authors: JunHwan Kwon, Oyun Kwon, KyeongTeak Oh, Jeongmin Kim, Cheung Soo Shin and Sun K. Yoo
    Citation: BioMedical Engineering OnLine 2022 21:64
  19. With the spread of COVID-19, telemedicine has played an important role, but tele-auscultation is still unavailable in most countries. This study introduces and tests a tele-auscultation system (Stemoscope) and...

    Authors: Muge Fan, Qiuli Wang, Jiaqi Liu, Lingyun Su, Bingjian Wang, Hai Xu, Qing Li and Zhi Zhang
    Citation: BioMedical Engineering OnLine 2022 21:63
  20. Aerosols and droplets are the transmission routes of many respiratory infectious diseases. The COVID-19 management guidance recommends against the use of nebulized inhalation therapy directly in the emergency ...

    Authors: Chen-Hsun Weng, Chia-Lung Kao, Po-Wei Chiu, Shao-Peng Huang, Yuh-Shin Kuo, Yu-Yuan Lin, I-Chen Lin, Hung-Chieh Chang, Chien-Hsin Lu and Chih-Hao Lin
    Citation: BioMedical Engineering OnLine 2022 21:62
  21. The age-related changes of gait symmetry in healthy children concerning individual joint and muscle activation data have previously been widely studied. Extending beyond individual joints or muscles, identifyi...

    Authors: Qiliang Xiong, Jinliang Wan, Shaofeng Jiang and Yuan Liu
    Citation: BioMedical Engineering OnLine 2022 21:61
  22. Remarkable work has been recently introduced to enhance the usage of Electromyography (EMG) signals in operating prosthetic arms. Despite the rapid advancements in this field, providing a reliable, naturalisti...

    Authors: Hend ElMohandes, Seif Eldawlatly, Josep Marcel Cardona Audí, Roman Ruff and Klaus-Peter Hoffmann
    Citation: BioMedical Engineering OnLine 2022 21:60
  23. Recently, transcatheter aortic valve replacement (TAVR) has been suggested as a less invasive treatment compared to surgical aortic valve replacement, for patients with severe aortic stenosis. Despite the atte...

    Authors: Paris Xenofontos, Reza Zamani and Mohammad Akrami
    Citation: BioMedical Engineering OnLine 2022 21:59
  24. Motor cortex stimulation applied as a clinical treatment for neuropathic disorders for decades. With stimulation electrodes placed directly on the cortical surface, this neuromodulation method provides higher ...

    Authors: Long Liu, Jiacheng Zhang, Jie Sun and Kedi Xu
    Citation: BioMedical Engineering OnLine 2022 21:58

    The Correction to this article has been published in BioMedical Engineering OnLine 2022 21:72

  25. Cardiac damage is the leading cause of death in uremic patients. This study aimed to evaluate the application of non-invasive myocardial work index (NIMWI) by echocardiography in assessing the left ventricular...

    Authors: Huizhen Zhu, Yanan Li, Cunying Cui, Danqing Huang, Yuanyuan Liu, Ruijie Liu, Qingqing Zhao, Ying Wang and Lin Liu
    Citation: BioMedical Engineering OnLine 2022 21:57
  26. Flat feet increase the risk of knee osteoarthritis and contribute to frailty, which may lead to worse life prognoses. The influence of the foot skeletal structure on flat feet is not yet entirely understood. F...

    Authors: Tomoko Yamashita, Kazuhiko Yamashita, Mitsuru Sato, Masashi Kawasumi and Shingo Ata
    Citation: BioMedical Engineering OnLine 2022 21:56
  27. Refractive error detection is a significant factor in preventing the development of myopia. To improve the efficiency and accuracy of refractive error detection, a refractive error detection network (REDNet) i...

    Authors: Daoliang Xu, Shangshang Ding, Tianli Zheng, Xingshuai Zhu, Zhiheng Gu, Bin Ye and Weiwei Fu
    Citation: BioMedical Engineering OnLine 2022 21:55
  28. CPT-11 (irinotecan) is one of the most efficient agents used for colorectal cancer chemotherapy. However, as for many other chemotherapeutic drugs, how to minimize the side effects of CPT-11 still needs to be ...

    Authors: Yongwei Liu, Xinghui Li, Renqun Pen, Wei Zuo, Ya Chen, Xiuying Sun, Juhua Gou, Qianwen Guo, Maoling Wen, Wuqi Li, Shuangjiang Yu, Hao Liu and Min Huang
    Citation: BioMedical Engineering OnLine 2022 21:53
  29. Diffusion-weighted (DW) imaging is a well-recognized magnetic resonance imaging (MRI) technique that is being routinely used in brain examinations in modern clinical radiology practices. This study focuses on ...

    Authors: Sahan M. Vijithananda, Mohan L. Jayatilake, Badra Hewavithana, Teresa Gonçalves, Luis M. Rato, Bimali S. Weerakoon, Tharindu D. Kalupahana, Anil D. Silva and Karuna D. Dissanayake
    Citation: BioMedical Engineering OnLine 2022 21:52
  30. Brain-controlled wheelchairs (BCWs) are important applications of brain–computer interfaces (BCIs). Currently, most BCWs are semiautomatic. When users want to reach a target of interest in their immediate envi...

    Authors: Kaixuan Liu, Yang Yu, Yadong Liu, Jingsheng Tang, Xinbin Liang, Xingxing Chu and Zongtan Zhou
    Citation: BioMedical Engineering OnLine 2022 21:50
  31. Ocular diseases are closely related to the physiological changes in the eye sphere and its contents. Using biomechanical methods to explore the relationship between the structure and function of ocular tissue ...

    Authors: Yali Zhao, Guohuang Hu, Yuwei Yan, Zhen Wang, Xiaohua Liu and Huanhuan Shi
    Citation: BioMedical Engineering OnLine 2022 21:49
  32. Authors: Chiang-Wen Lee, Ming-Hsien Chiang, Wen-Chun Wei, Shu-Hsien Liao, Yen-Bin Liu, Kuan-Chih Huang, Kuen-Lin Chen, Wen-Cheng Kuo, Yuan-Ching Sung, Ting-Yuan Chen, Ju-Fang Liu, Yao-Chang Chiang, Hsin-Nung Shih, Kuo-Ti Peng and Jen-Jie Chieh
    Citation: BioMedical Engineering OnLine 2022 21:48

    The original article was published in BioMedical Engineering OnLine 2022 21:38

  33. To assess the feasibility and clinical utility of artificial intelligence (AI)-based screening for diabetic retinopathy (DR) and macular edema (ME) by combining fundus photos and optical coherence tomography (...

    Authors: Rui Liu, Qingchen Li, Feiping Xu, Shasha Wang, Jie He, Yiting Cao, Fei Shi, Xinjian Chen and Jili Chen
    Citation: BioMedical Engineering OnLine 2022 21:47
  34. Advances in sports medicine, rehabilitation applications and diagnostics of neuromuscular disorders are based on the analysis of skeletal muscle contractions. Recently, medical imaging techniques have transfor...

    Authors: Hazrat Ali, Johannes Umander, Robin Rohlén, Oliver Röhrle and Christer Grönlund
    Citation: BioMedical Engineering OnLine 2022 21:46
  35. Abnormal prolongation in the QT interval or long QT syndrome (LQTS) is associated with several cardiac complications such as sudden infant death syndrome (SIDS). LQTS is believed to be linked to genetic mutati...

    Authors: Namareq Widatalla, Kiyoe Funamoto, Motoyoshi Kawataki, Chihiro Yoshida, Kenichi Funamoto, Masatoshi Saito, Yoshiyuki Kasahara, Ahsan Khandoker and Yoshitaka Kimura
    Citation: BioMedical Engineering OnLine 2022 21:45
  36. Dysautonomia plays an ancillary role in the pathogenesis of Chronic Chagas Cardiomyopathy (CCC), but is the key factor causing digestive organic involvement. We investigated the ability of heart rate variabili...

    Authors: Luiz Eduardo Virgilio Silva, Henrique Turin Moreira, Marina Madureira de Oliveira, Lorena Sayore Suzumura Cintra, Helio Cesar Salgado, Rubens Fazan Jr, Renato Tinós, Anis Rassi Jr, André Schmidt and J. Antônio Marin-Neto
    Citation: BioMedical Engineering OnLine 2022 21:44
  37. Cutaneous electrogastrography (EGG) is a non-invasive technique that detects gastric bioelectrical slow waves, which in part govern the motility of the stomach. Changes in gastric slow waves have been associat...

    Authors: Atchariya Sukasem, Stefan Calder, Timothy R. Angeli-Gordon, Christopher N. Andrews, Gregory O’Grady, Armen Gharibans and Peng Du
    Citation: BioMedical Engineering OnLine 2022 21:43
  38. It is known that inflammatory bowel disease is the result of a defective immune system, and immunotherapy and biological therapy have gradually become important means to treat it. This paper focused on the bib...

    Authors: Jia-Qi Xiong, Yun-Feng Fu, Jian-Hao Qiu, Wang-Di Liao, Ling-Yu Luo and Si-Hai Chen
    Citation: BioMedical Engineering OnLine 2022 21:42
  39. Considering the estimate that thyroid cancer will become the fourth most prevalent type of tumor, improving its diagnosis is a necessity. The gold standard for evaluating thyroid nodules is ultrasound followed...

    Authors: Viviane Magas Bittencourt de Camargo, Leandra Ulbricht, Jose Carlos Pereira Coninck, Wagner Luis Ripka and Humberto Remigio Gamba
    Citation: BioMedical Engineering OnLine 2022 21:41
  40. The minimum variance (MV) beamformer can significantly improve the image resolution in ultrasound imaging, but it has limited performance in noise reduction. We recently proposed the covariance matrix-based st...

    Authors: Yuanguo Wang, Yadan Wang, Mingzhou Liu, Zhengfeng Lan, Chichao Zheng and Hu Peng
    Citation: BioMedical Engineering OnLine 2022 21:40
  41. Hypertension is known as a major factor for global mortality. We aimed to investigate the role of Cullin3 (CUL3) in the regulation of hypertension.

    Authors: Jian Shen, Youqi Li, Menghao Li, Zhiming Li, Huantang Deng, Xiongwei Xie and Jinguang Liu
    Citation: BioMedical Engineering OnLine 2022 21:39
  42. Although the powerful clinical effects of radiofrequency and microwave ablation have been established, such ablation is associated with several limitations, including a small ablation size, a long ablation tim...

    Authors: Chiang-Wen Lee, Ming-Hsien Chiang, Wen-Chun Wei, Shu-Hsien Liao, Yen-Bin Liu, Kuan-Chih Huang, Kuen-Lin Chen, Wen-Cheng Kuo, Yuan-Ching Sung, Ting-Yuan Chen, Ju-Fang Liu, Yao-Chang Chiang, Hsin-Nung Shih, Kuo-Ti Peng and Jen-Jie Chieh
    Citation: BioMedical Engineering OnLine 2022 21:38

    The Correction to this article has been published in BioMedical Engineering OnLine 2022 21:48

  43. Near-infrared (NIR) autofluorescence detection is an effective method for identifying parathyroid glands (PGs) in thyroidectomy or parathyroidectomy. Fiber optical probes provide quantitative autofluorescence ...

    Authors: Wei Chen, Xiaopeng Ma, Pengfei Shao, Peng Liu and Ronald X. Xu
    Citation: BioMedical Engineering OnLine 2022 21:37
  44. Despite numerous clinical trials and pre-clinical developments, the diagnosis of cracked tooth, especially in the early stages, remains a challenge. Cracked tooth syndrome is often accompanied by dramatic pain...

    Authors: Juncheng Guo, Yuyan Wu, Lizhi Chen, Shangbin Long, Daqi Chen, Haibing Ouyang, Chunliang Zhang, Yadong Tang and Wenlong Wang
    Citation: BioMedical Engineering OnLine 2022 21:36
  45. Low- to high-energy impact trauma may cause from small fissures up to extended bone losses, which can be classified as closed or opened injuries (when they are visible at a naked eye).

    Authors: Wally auf der Strasse, Daniel Prado Campos, Celso Júnio Aguiar Mendonça, Jamil Faissal Soni, Joaquim Mendes and Percy Nohama
    Citation: BioMedical Engineering OnLine 2022 21:35